BIOTECHNOLOGY

GEN – TREND, s.r.o.

Contact details: Dolní 2 370 04 České Budějovice www.gentrend.cz
Laboratory: Hůry 149 373 71 Rudolfov
Head: Ing. Václav Filistein tel.: +420 602 270 809 e-mail: filistein@gentrend.cz

ACTIVITY SUBJECT

  • research and development: molecular biological diagnostics, molecular biological techniques in biotechnology
  • laboratory of molecular biology (registered private facility ): diagnostics of periodontal diseases, detection of cariogenic bacteria, detection of tick-borne pathogens in samples of ticks, services in the field of molecular biology for veterinarians and breeders (sex determination in birds, detection of selected pathogens, diagnostics of periodontitis in dogs, etc.), screening PCR testing, cloning and production of recombinant proteins.

     

KEYWORDS

  • molecular biology
  • periodontitis
  • tick
  • Lyme Borreliosis
  • tick-borne encephalitis
  • anaplasmosis
  • PCR
  • recombinant proteins
  • innovation

OBJECTIVES

  • provide high-quality services and in the most complex way possible
  • enhance the quality and range of services offered so that it is possible to detach a separate research and development department
  • engage in research projects as an investigator, cooperating institution or contractor
  • continue expanding the network of cooperating institutions both from the private and public research sector

RESEARCH ACTIVITIES

  • molecular biological diagnosis in dentistry and veterinary dentistry
  • development of molecular-biological biotechnological applications

EQUIPMENT AT THE WORKPLACE

  • The laboratory is fully equipped to be able to carry out most molecular-biological techniques (PCR box, biohazard box, PCR cyclers, real-time PCR, electrophoreses, hybridization machine, a documentation system for chemiluminescence), and has equipment for work with infectious specimens (biohazard boxes, hygiene loop) and for “medium-volume” production of recombinant proteins (fermentor 7 l, chromatograph, centrifuges). The laboratory has a well-established certified system of quality management in accordance with the standard CSN EN ISO 13485:2012.

REFERENCE

Project solved:

  • 2004-2006: Research and development of a molecular-biological diagnostic set for rapid detection of periodontal pathogens (Ministry of Industry and Trade, IMPULSE)
  • 2008-2010: Supporting the export of the VariOr®Dento test (Ministry of Industry and Trade, OPEI-MARKETING)
  • 2008-2011: Innovation in VariOr®Dento biochip and in the production of antigens (Ministry of Industry and Trade, OPEI-INNOVATION)
  • 2011-2013: Innovation of a diagnostic product – expanding the methods for the determination of periodontal pathogens (Ministry of Industry and Trade, OPEI-INNOVATION)

Results:

  • VariOr Dento – DNA diagnostics of periodontitis (7 periodontal pathogens + beta-lactam resistance)
  • VariOr Dento Plus – DNA diagnostics of periodontitis (11 periodontal pathogens + beta-lactam resistance)

 

COOPERATING INSTITUTIONS

Academic:

  • Faculty of Science – University of South Bohemia in České Budějovice (České Budějovice, CZ)
  • Faculty of Science, Charles University in Prague (Prague, CZ)
  • Faculty of Agriculture, University of South Bohemia in České Budějovice (České Budějovice, CZ)
  • Biology Centre ASCR in České Budějovice (České Budějovice, CZ)
  • Faculty of Pharmacy, Charles University in Hradec Králové (Hradec Králové,CZ)
  • Center of Cardiovascular and Transplantation Surgery, Brno (Brno, CZ)
  • Institute of Chemical Technology Prague (Prague, CZ)
  • Biotechnological Centre of the Faculty of Agriculture – University of South Bohemia in České Budějovice (České Budějovice, CZ)

Companies:

  • South Bohemian Agency for Support to Innovative Enterprising (České Budějovice, CZ)
  • ENVISAN-GEM,a.s. (České Budějovice, CZ)
  • ANECLAB s.r.o. (České Budějovice, CZ)
  • Vidia, spol. s r.o.  (Prague, CZ)
  • Biologicals s.r.o.  (Prague, CZ)
  • Synlab.cz s.r.o.  (Prague, CZ)
  • ECO trend Research centre s.r.o.  (Prague, CZ)
  • Scandi Biomedical (DK)

WE ARE LOOKING FOR

  • ideas or research results applicable in practice – especially in the field of molecular diagnostics within human and veterinary medicine
  • opportunities to participate in applied research projects with the ultimate goal to introduce the finished product to the market
  • possibilities of cooperation in the area of services currently offered to companies (e.g. analysis of periodontal pathogens within the scope of research projects, testing the treatment methods, etc.)

WE OFFER

  •  services in the field of molecular biology and molecular diagnostics, including the development of custom-made diagnostics
  • cooperation in projects of applied research and development as a private sector partner